发明名称 New-quanidino-thiazol compounds, their preparation, and use as intermediates of famotidine process.
摘要 New 2-guanidino-thiazol compounds with the general formulas <CHEM> where R DEG represents an hydrogen atom or an alkyl group of low molecular weight, m = 2 to 7, n = 2 to 4, and <CHEM> being R an alkyl group of low molecular weight and that may contain from one N-alkylsilyl group, that are important intermediates for the famotidine preparation, medically used as inhibitor of the gastric secretion.
申请公布号 EP0322335(A1) 申请公布日期 1989.06.28
申请号 EP19880500031 申请日期 1988.03.23
申请人 CENTRO MARGA PARA LA INVESTIGACION S.A. 发明人 BALLESTER RODES,MONTSERRAT;PALOMO NICOLAU , FRANSISCO EUGENIO;PALOMO COLL, ANTONIO LOUIS
分类号 A61K31/425;C07D;C07D277/18;C07D277/28;C07D277/48;C07D451/00;C07D471/04;C07D487/04;C07F7/10 主分类号 A61K31/425
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