发明名称 |
New-quanidino-thiazol compounds, their preparation, and use as intermediates of famotidine process. |
摘要 |
New 2-guanidino-thiazol compounds with the general formulas <CHEM> where R DEG represents an hydrogen atom or an alkyl group of low molecular weight, m = 2 to 7, n = 2 to 4, and <CHEM> being R an alkyl group of low molecular weight and that may contain from one N-alkylsilyl group, that are important intermediates for the famotidine preparation, medically used as inhibitor of the gastric secretion.
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申请公布号 |
EP0322335(A1) |
申请公布日期 |
1989.06.28 |
申请号 |
EP19880500031 |
申请日期 |
1988.03.23 |
申请人 |
CENTRO MARGA PARA LA INVESTIGACION S.A. |
发明人 |
BALLESTER RODES,MONTSERRAT;PALOMO NICOLAU , FRANSISCO EUGENIO;PALOMO COLL, ANTONIO LOUIS |
分类号 |
A61K31/425;C07D;C07D277/18;C07D277/28;C07D277/48;C07D451/00;C07D471/04;C07D487/04;C07F7/10 |
主分类号 |
A61K31/425 |
代理机构 |
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地址 |
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