发明名称 |
Enhancers for the transdermal flux of certain 1,4-Dihydropyridine derivatives. |
摘要 |
<p>The transdermal flux rates of 1,4-dihydropyridine derivatives, such as nilvapidine and its enantiomers may be increased by the use of a solvent vehicle which comprises dioctyl adipate, isopropyl myristate, benzyl alcohol, diisopropyl adipate, a mixture of 5 to 50% ethyl alcohol and 95-50% of diisopropyl adipate, or a mixture of any of the foregoing.</p> |
申请公布号 |
EP0321636(A2) |
申请公布日期 |
1989.06.28 |
申请号 |
EP19880107452 |
申请日期 |
1988.05.10 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
PAWELCHAK, JOHN MICHAEL;LAWTER, JAMES RONALD |
分类号 |
A61K31/395;A61K31/44;A61K31/455;A61K47/06;A61K47/10;A61K47/14;A61K47/16;A61K47/18 |
主分类号 |
A61K31/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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