发明名称 10-aryl-1,8-dihydroxy-9-anthrones and their esters, process for preparing same, and use of same in human and veterinary medicine and in cosmetics
摘要 Mono, di and tri-esters of 1,8-dihydroxy-10-phenyl-9-anthrone or -9-anthranol have the formula <IMAGE> (I) wherein p is 0 or 1, (a) when p=0, t=1 and R2 represents hydrogen or -COR3, (b) when p=1, t=0 and R1 and R2 each independently represent hydrogen or -COR3, R3 represents linear or branched alkyl having 1-17 carbon atoms, cycloalkyl, phenyl or phenyl substituted by lower alkyl, lower alkoxy, halogen, a nitro function, -CF3 or a hydroxyl function, and mixtures of said esters. These esters are prepared by reacting 1,8-dihydroxy-10-phenyl-9-anthrone with an activated form of an acid. The esters are useful in human or veterinary medicine and in cosmetic compositions.
申请公布号 US4843097(A) 申请公布日期 1989.06.27
申请号 US19880176974 申请日期 1988.04.04
申请人 GROUPEMENT D'INTERET ECONOMIQUE DIT: CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. 发明人 SHROOT, BRAHAM;LANG, GERARD;MAIGNAN, JEAN;RESTLE, SERGE;HENSBY, CHRISTOPHER;COLIN, MICHEL
分类号 A61K8/37;A61K31/215;A61Q5/00;A61Q7/00;A61Q19/00;C07D277/24;C07D333/22;C07D333/24 主分类号 A61K8/37
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