发明名称 |
Heterohybridoma screening method |
摘要 |
Human-nonhuman heterohybridomas capable of expressing IgM type antibodies can be screened to select hybridomas expressing IgM antibodies comprising human J chain components. Method comprises contacting separate samples of IgM antibodies (or IgM J chain components) from a given cell line with anti-human J chain antibodies and anti-non-human J chain antibodies to determine which antibody complexes with the J chain component of the samples, thereby identifying and permitting the early selection of a heterohybridoma expressing IgM having a human J chain component.
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申请公布号 |
US4842998(A) |
申请公布日期 |
1989.06.27 |
申请号 |
US19870120047 |
申请日期 |
1987.11.09 |
申请人 |
MILES INC. |
发明人 |
MENG, Y. GLORIA;TRAWINSKI, JURGEN |
分类号 |
C12N5/26;G01N33/68 |
主分类号 |
C12N5/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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