发明名称 METHOD OF CARBOXY-ALKENE ACID'S DERIVATIVES PRODUCTION
摘要 Cephems and analogues of formula (I) are new. R = aryl or heterocyclyl; R1 = H or halogen; R2 = single bond, alkylene, oxa-alkylene or thia-alkylene- R3, R6 = H, salt-forming atom or gp. or ester-forming gp.; R4 = H or MeO; R5 = H or a 3-substituent as found in cephalosporins; X = O, S or SO. Provided that when R2 = thia-alkylene, then R1 = halogen. - Intermediates of formula (II) are new.
申请公布号 CS8700445(A2) 申请公布日期 1989.06.13
申请号 CS19870000445 申请日期 1987.01.21
申请人 SHIONOGI AND CO. LTD.,JP 发明人 HAMASHIMA YOSHIO,JP
分类号 A61K31/545;C07C57/13;C07D265/12;C07D279/08;C07D501/20;C07D501/59;(IPC1-7):C07C57/13 主分类号 A61K31/545
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