发明名称 |
TETRA-AND PENTAPEPTIDE CONTAINING LYS-ARG-ASP SEQUENCE AND USE THEREOF AS DRUG ESPECIALLY, AS HYPERTROMBIN AGENT |
摘要 |
The peptides according to the invention are of the following general formula I: Z-Lys-Arg-Asp-X-Y (I) wherein: X is the residue of one of the 20 common aminoacids in the L-configuration, Y is hydroxyl or the C-terminal residue of one of the 20 common aminoacids in the L-configuration, Z is acetyl, hydrogen or the N-terminal residue of one of the 20 common aminoacids in the L-configuration, as the case may be N-acetylated, whereby it is understood that: when Y is the C-terminal residue of one of the 20 common aminoacids in the L-configuration, Z is acetyl or hydrogen and X can in all cases be different from Y and from Z. Application to the preparation of anti-thrombotic medicines. |
申请公布号 |
JPH01149799(A) |
申请公布日期 |
1989.06.12 |
申请号 |
JP19880271086 |
申请日期 |
1988.10.28 |
申请人 |
ANSUCHI DE BUETSUSOO E DU SAN;CENTRE NATL RECH SCIENT <CNRS> |
发明人 |
PIEERU JIYORU;ANNUUMARI FUIA;KUROODEINU SORIA;SHIRUBUIANU REEBUIITOREDANO;SANGUHAMITORA RAHA;ERIZABESU MAZOWAIE;RIYUUDOBUIKU DORUE |
分类号 |
C07K14/81;A61K38/55;A61P7/02;C07K5/10;C07K7/06;C07K14/75 |
主分类号 |
C07K14/81 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|