发明名称 STABILIZATION OF PERGOLIDE COMPOUND
摘要 PURPOSE: To obtain a pergolide compound-containing pharmaceutical composition that has strong dopamine activity and is stabilized to photodegradation useful for treatment of a hyperprolactin blood disease. CONSTITUTION: This pergolide compound-containing pharmaceutical composition suitable for oral administration contains pergolide and its salts as an active ingredient, a stabilizer selected from polyvinyl pyrrolidone,α-tocopherol succinate and propyl gallate, and one or more excipients. When polyvinyl pyrrolidone is used for this composition, it is added in a quantity of 0.3-2wt.% to the whole weight of the composition.
申请公布号 JPH01146821(A) 申请公布日期 1989.06.08
申请号 JP19880267000 申请日期 1988.10.20
申请人 ELI LILLY & CO 发明人 JIEIMUZU UIRIAMU KONAIN;JIYUURIAN RARII SUTOWAAZU
分类号 A61K31/48;A61K47/00;A61K47/14;A61K47/22;A61K47/32;A61P25/00;A61P43/00 主分类号 A61K31/48
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