发明名称 |
PROCESS FOR ISOLATING AND PURIFYING THE HEPATITIS B SURFACE ANTIGEN |
摘要 |
The supernatant of engineered yeast cells having produced hepatitis B surface antigaen and disrupted in the presence of a polysorbate non-ionic detergent is clarified by addition of urea and adsorbed on colloidal silica from which the purified antigen is desorbed with a low ionic strength buffer supplemented with urea and a polysorbate non-ionic detergent. |
申请公布号 |
DE3663108(D1) |
申请公布日期 |
1989.06.08 |
申请号 |
DE19863663108 |
申请日期 |
1986.05.21 |
申请人 |
SMITH KLINE - RIT SOCIETE ANONYME DITE: |
发明人 |
VAN WIJNENDAELE, FRANS;SIMONET, GUY |
分类号 |
A61K39/29;C07K14/02;(IPC1-7):A61K39/29 |
主分类号 |
A61K39/29 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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