发明名称 POLYENFORENINGAR
摘要 Compounds of the formula <IMAGE> wherein R<1> is a group of the formula <IMAGE> R<2> is hydroxy, lower-alkoxy, amino, mono-(lower-alkyl)amino or di-(lower-alkyl)- amino, R<3> is lower-alkyl or halogen, R<4> is lower-alkyl, R<5> is lower-alkoxy, R<6> is hydrogen or lower-alkyl and R<7> is lower-alkyl or halogen, and pharmaceutically acceptable salts of the carboxylic acids of formula I can be used for the treatment of neo-plasms and dermatoses. The compounds of formula I can be obtained by forming the side-chain from corresponding cyclic and aliphatic for components by means of a Wittig or Horner reaction.
申请公布号 SE8303539(L) 申请公布日期 1983.12.25
申请号 SE19830003539 申请日期 1983.06.20
申请人 HOFFMANN LA ROCHE 发明人 KREBS E P
分类号 C07C69/608;A61K31/075;A61K31/085;A61K31/16;A61K31/165;A61K31/185;A61K31/19;A61K31/20;A61K31/215;A61K31/22;A61K31/23;A61P29/00;A61P35/00;C07C51/00;C07C57/26;C07C57/30;C07C57/42;C07C57/50;C07C59/64;C07C59/74;C07C59/90;C07C67/00;C07C69/587;C07C69/618;C07C69/734;C07C69/738;C07C231/00;C07C231/02;C07C231/12;C07C233/02;C07C233/10;C07C233/11;C07C233/12;C07C233/65;C07C401/00;C07C403/00;C07C403/20;(IPC1-7):C07C57/42;C07C57/48;C07C69/52;C07C69/61;C07C103/13 主分类号 C07C69/608
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