| 发明名称 |
IMPROVED RICIN MOLECULES AND RICIN TOXIN CONJUGATES |
| 摘要 |
Novel ricin molecules having ricin-type activity and targeted toxin conjugates containing the same are disclosed. The molecules are characterized by modification within the lectin binding regions of the B chain. Methods for making these molecules and conjugates are disclosed as are the therapeutic compositions containing the same. |
| 申请公布号 |
WO8904839(A1) |
申请公布日期 |
1989.06.01 |
| 申请号 |
WO1988US04238 |
申请日期 |
1988.11.23 |
| 申请人 |
GENETICS INSTITUTE, INC. |
发明人 |
BROWN, EUGENE, L.;JONES, SIMON |
| 分类号 |
C12N15/00;A61K38/00;A61K39/395;A61P35/00;C07K14/415;C07K14/42;C07K14/495;C07K14/52;C07K14/525;C07K14/53;C07K14/535;C07K14/54;C07K14/545;C07K14/55;C07K16/00;C07K19/00;C12P21/02;C12R1/91;(IPC1-7):C07K13/00 |
主分类号 |
C12N15/00 |
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