METHOD OF OBTAINING NOVEL DERIVATIVES OF THREE-RING OXINDOLOCARBONAMIDE

摘要

PCT No. PCT/US84/01371 Sec. 371 Date Apr. 2, 1986 Sec. 102(e) Date Apr. 2, 1986 PCT Filed Aug. 24, 1984 PCT Pub. No. WO86/01510 PCT Pub. Date Mar. 13, 1986.Tricyclic oxindole carboxamides, prepared by (a) reaction of an isocyanate with the basic ring system or (b) ammonolysis of a corresponding alkyl ester, are non-steroidal antiinflammatory agents useful in the treatment of rheumatoid arthritis.