ACINO-FOETAL DIFFERENTIATION PROTEINS ASSOCIATED WITH CANCER OF THE PANCREAS, ANTISERUM AND MONOCLONAL ANTIBODIES AGAINST THESE PROTEINS AND PROCESSES FOR THEIR PREPARATION

摘要

PCT No. PCT/FR85/00268 Sec. 371 Date May 29, 1986 Sec. 102(e) Date May 29, 1986 PCT Filed Sep. 30, 1985 PCT Pub. No. WO86/02081 PCT Pub. Date Apr. 10, 1986.The invention relates to acino-fetal differentiation proteins associated with cancer of the pancreas, these proteins being mannoside-containing glycoproteins of average apparent molecular mass chosen from: 120 KD, 94 KD and 58 KD. The invention also relates to a method for preparing these proteins, an antiserum against these proteins and the method for preparation thereof, monoclonal antibodies against these proteins and the method for preparation thereof, and compositions for diagnostic or therapeutic use containing these proteins or antibodies.