| 摘要 |
<p>There are disclosed anti-tumor prodrug compounds that are (a) disulfide benzylcarbamate derivatives of amino (primary and secondary) containing anti-tumor drugs, and (b) disulfide benzylcarbonate derivatives of hydroxyl containing anti-tumor drugs. The prodrug compounds release active, free drug as a result of undergoing reductive cleavage of the disulfide moiety and subsequent chemical fragmentation.</p> |
