发明名称 Drug-monoclonal antibody conjugates.
摘要 <p>There is disclosed a drug-monoclonal antibody conjugate wherein the antibody is linked to a antitumor drug using disulfide benzyl carbamate or carbonate as the linker. The conjugate is used for delivering an active antitumor drug to the site of tumor cells in a mammal by administering the drug-monoclonal antibody conjugate.</p>
申请公布号 EP0317957(A2) 申请公布日期 1989.05.31
申请号 EP19880119419 申请日期 1988.11.22
申请人 BRISTOL-MYERS COMPANY 发明人 SENTER, PETER D.
分类号 C12P21/08;A61K39/395;A61K47/48;A61P35/00;C07K16/00 主分类号 C12P21/08
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