FOERFARANDE FOER FRAMSTAELLNING AV EN FOER INFUSIONSAENDAMAOL AVSEDD STABILISERAD INSULINLOESNING, SOM HAR EN FOERHOEJD ZINKHALT.

摘要

Novel pharmaceutical solutions of dissolved insulin having improved physical stability prepared by incorporating therein an essentially ionized zinc salt in a concentration corresponding to a content of zinc ions at the disposal of the insulin of more than 4 Zn2+/hexamer insulin preferably 4.2-4.5 Zn2+/hexamer insulin. The solutions exhibit a stability factor exceeding 5. The novel insulin solutions are particularly adapted for use in continuous insulin delivery equipment.