| 摘要 |
PCT No. PCT/SE95/01459 Sec. 371 Date May 20, 1997 Sec. 102(e) Date May 20, 1997 PCT Filed Dec. 5, 1995 PCT Pub. No. WO96/18423 PCT Pub. Date Jun. 20, 1996A process for coating of an intraocular lens to impart tissue compatibility thereto, comprising the steps: a) priming said lens using a solution of a polyamine; b) coating the lens treated in step a) above with a solution of a periodate-oxidized polysaccharide selected from heparin, heparain sulphate, and chondroitin sulphate to stabilize said polyamine by covalent and/or ionical cross-linking; c) coating the lens treated in step b) above with a solution of a polyamine; and d) coating the lens treated according to step c) above with a solution of a periodate-oxidized polysaccharide selected from heparin, heparain sulphate, and chondroitin sulphate in the presence of a cyanoborohydride to convert formed labile Schiff's bases to stable secondary amines. |
