发明名称 Hydroquinone derivative and pharmaceutical use thereof
摘要 <p>Disclosed is a hydroquinone derivative or a pharmaceutically acceptable salt thereof, the hydroquinone derivative being represented by formula (I): &lt;CHEM&gt; wherein R&lt;1&gt; is a phenyl group which is unsubstituted or substituted with a substituent or substituents each independently selected from the group consisting of a halogen atom, a C1-4 alkyl group and a C1-4 alkoxy group; R&lt;2&gt; is a hydrogen atom or a C1-4 alkyl group; each of R&lt;3&gt; and R&lt;4&gt; is independently a hydrogen atom or a C1-4 alkyl group; R&lt;5&gt; is a hydrogen atom or a C1-4 alkyl group; each of R&lt;6&gt;, R&lt;7&gt; and R&lt;8&gt; is independently a hydrogen atom or a C1-4 alkyl group; P is a hydroxyl group; Q is a hydroxyl group, a C1-4 alkoxy group, a C1-18 acyloxy group or an oxo group; P may form together with Q an ether bond; R is a hydroxyl group, a C1-4 alkoxy group, a C1-18 acyloxy group or an oxo group, provided that when one of said Q and said R is an oxo group, the other is also an oxo group; X is a single bond, an -NR&lt;10&gt;- group or a -CH2-NR&lt;10&gt;- group in which R&lt;10&gt; is a hydrogen atom or a C1-4 alkyl group; Y is a methylene group or a carbonyl group; and dotted bonds in a six membered ring represent that said six membered ring has the maximum number of double bonds.</p>
申请公布号 EP0831092(A2) 申请公布日期 1998.03.25
申请号 EP19970250280 申请日期 1997.09.17
申请人 JAPAN ENERGY CORPORATION 发明人 ISOBE, YOSHIAKI;GOTO, YUSO;TOBE, MASANORI;TAKAHASHI, OSAMU
分类号 C07D239/54;C07D239/545;C07D405/12;(IPC1-7):C07D405/12;A61K31/505 主分类号 C07D239/54
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