| 发明名称 |
GUANIDINOBENZOIC ESTER DERIVATIVE, A PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
| 摘要 |
A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. <IMAGE> wherein X represents a group of the formula: <IMAGE> in which Y is a group of the formula: -(CH2)m-, m being an integer of 2 or 3, <IMAGE> <IMAGE> or a group of the formula: -OR in which R is a hydrogen atom or a lower alkyl group, and n represents an integer of 1 to 5. |
| 申请公布号 |
DE3662883(D1) |
申请公布日期 |
1989.05.24 |
| 申请号 |
DE19863662883 |
申请日期 |
1986.12.22 |
| 申请人 |
EISAI CO., LTD. |
发明人 |
SOUDA, SHIGERU;SHIMOMURA, NAOYUKI;UEDA, NORIHIRO;MIYAZAWA, SHUHEI;YAMANAKA, TAKASHI;MIYAMOTO, KANAME;HISHINUMA, IEHARU;NAGAKAWA, JUNICHI;NAGAOKA, NAOKO;KAWASHIMA, HIDETOSHI;KAWATA, TSUTOMU;NAGAOKA, JUNSAKU;WAKABAYASHI, TSUNEO |
| 分类号 |
A61K31/235;A61K31/245;A61K31/40;A61K31/4015;A61K31/403;A61K31/4035;A61K31/42;A61K31/421;A61K31/445;A61P1/00;A61P7/02;A61P7/04;A61P43/00;C07C67/00;C07C313/00;C07C319/20;C07C323/20;C07D207/40;C07D207/404;C07D207/408;C07D209/48;C07D209/76;C07D211/76;C07D211/88;C07D263/44;(IPC1-7):C07C149/437 |
主分类号 |
A61K31/235 |
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