PLASMID FOR TRANSFORMING BACTERIAL HOST TO RENDER IT CAPABLE OF POLYPEPTIDE EXPRESSION

摘要

Recombinant microbial cloning vehicles comprising heterologous DNA coding for the expression of mammalian hormones (e.g., somatostatin) and other polypeptides, including plasmids suited for the transformation of bacterial hosts are prepared. The latter incorporate a regulon homologous to the host in its untransformed state, in reading phase with the structural gene for the heterologous DNA.