Biphenyl derivatives, preparation method, pharmaceutical compositions comprising them and use.

摘要

Biphenyl derivative of the formula: <CHEM> wherein R<1> is hydrogen atom or a lower alkoxycarbonyl group and R<2> is a lower alkoxycarbonyl group, or R<1> and R<2> are combined together to form a group of the formula: <CHEM> each of R<3> and R<4> is a lower alkoxy group; and Ring A is a substituted or unsubstituted sulfur-containing or nitrogen-containing heterocyclic ring, and a pharmaceutically acceptable salt thereof are disclosed. Said biphenyl derivative (I) and its salt have excellent hypolipidemic activity and are useful for treatment or prophylaxis of hyperlipidemia and/or arteriosclerosis.