发明名称 |
NOR-CHOLANIC ACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
<p>PCT No. PCT/EP87/00006 Sec. 371 Date Oct. 29, 1987 Sec. 102(e) Date Oct. 29, 1987 PCT Filed Jan. 7, 1987 PCT Pub. No. WO87/04166 PCT Pub. Date Jul. 16, 1987. <IMAGE> I Compounds I (either R1=OH, C1-C4 alkoxy and R2=H, C1-C4 alkyl, or R1+R2=a chemical bond; R3=an aminodeoxy or aminodideoxy or aminotrideoxy sugar residue of the D and L series, the glycosidic linkage being alpha or beta : and either R4=OH and R5=H or R4+R5=a chemical bond) and their pharmaceutically acceptable salts are useful as antihypertensive agents. Their preparation and use as well as pharmaceutical compositions containing them are also described.</p> |
申请公布号 |
EP0253859(B1) |
申请公布日期 |
1989.05.24 |
申请号 |
EP19870900806 |
申请日期 |
1987.01.07 |
申请人 |
FARMITALIA CARLO ERBA S.R.L. |
发明人 |
CHIODINI, LAURA;GOBBINI, MAURO;MANTEGANI, SERGIO;RUGGIERI, DANIELA;TEMPERILLI, ALDEMIO;TRAQUANDI, GABRIELLA;FERRARI, PATRIZIA |
分类号 |
A61K31/575;C07J1/00;C07J41/00 |
主分类号 |
A61K31/575 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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