Triazole antifungal agents.

摘要

Triazole antifungal agents of the formula:-
<CHEM>
and their O-esters and O-ethers;
where R is naphthyl, biphenylyl or phenyl optionally substituted by 1 to 3 substituents each independently selected from halo, CF3, C1-C4 alkyl and C1-C4 alkoxy; and R<1> is
-@NR<2>R<3>

or -@R<3>

where X is O or S;
R<2> is hydrogen of C1-C4 alkyl; and
R<3> is hydrogen, C1-C4 alkyl, C3-C6 cycloalkyl, aryl, aralkyl, or heteroaryl; or
R<2> and R<3> taken together with the N atom to which they are attached represent a 1-pyrrolidinyl or piperidino group; and their pharmaceutically acceptable salts. The compounds are useful as human veterinary and agricultural fungicides.