发明名称 POLYCYCLICAMINES WITH PSYCHOTROPIC ACTIVITY
摘要 There are disclosed compounds of formula (I), wherein R represents (II), (III) or (IV), where X is lower alkylene, vinylene or O; Y is lower alkylene or vinylene; n is 2 - 4; the dotted line represents an optional double bond; m is 1 - 3; A is phenyl, benzoyl, pyridinyl, quinolinyl or quinoxalinyl, or any of the foregoing substituted with lower alkyl, lower alkoxy, halo, cyano, nitro or trifluoromethyl; or when m is > 1, A represents the grouping (V), where B is phenyl, pyrimidinyl, pyridinyl or pyrazinyl, or any of the foregoing substituted with lower alkyl, lower alkoxy, halo, cyano, nitro or trifluoromethyl, with the proviso that where R is (II), A is other than unsubstituted or substituted benzoil or pyridinyl; and the pharmacologically acceptable salts thereof and their use as antipsychotic/anxiolytic and antidepressant agents and in the treatment of sexual dysfunction and having a low liability for extrapyramidal side effects.
申请公布号 WO8904311(A1) 申请公布日期 1989.05.18
申请号 WO1988US03924 申请日期 1988.11.10
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 ABOU-GHARBIA, MAGID, A.;PATEL, USHA, R.
分类号 C07D209/72;C07D401/06;C07D487/08;(IPC1-7):C07D401/06;C07D401/14;C07D403/06;C07D403/14 主分类号 C07D209/72
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