摘要 |
There are disclosed compounds of formula (I), wherein R represents (II), (III) or (IV), where X is lower alkylene, vinylene or O; Y is lower alkylene or vinylene; n is 2 - 4; the dotted line represents an optional double bond; m is 1 - 3; A is phenyl, benzoyl, pyridinyl, quinolinyl or quinoxalinyl, or any of the foregoing substituted with lower alkyl, lower alkoxy, halo, cyano, nitro or trifluoromethyl; or when m is > 1, A represents the grouping (V), where B is phenyl, pyrimidinyl, pyridinyl or pyrazinyl, or any of the foregoing substituted with lower alkyl, lower alkoxy, halo, cyano, nitro or trifluoromethyl, with the proviso that where R is (II), A is other than unsubstituted or substituted benzoil or pyridinyl; and the pharmacologically acceptable salts thereof and their use as antipsychotic/anxiolytic and antidepressant agents and in the treatment of sexual dysfunction and having a low liability for extrapyramidal side effects. |