发明名称 |
METHOD FOR INCREASING MANIFESTATION OF POLYPEPTIDE DURING CULTURE OF RECOMBINATION CELL |
摘要 |
<p>Viable cell proportions and total cell densities in recombinant eukaryotic cell cultures are increased by transfecting a eukaryotic host cell with nucleic acid encoding a desired polypeptide and with an oncogene. Transfectant cultures are screened thereafter for the expression of elevated quantities of the desired polypeptide as compared to expression from the parent host cell.</p> |
申请公布号 |
JPH01120300(A) |
申请公布日期 |
1989.05.12 |
申请号 |
JP19880227338 |
申请日期 |
1988.09.09 |
申请人 |
GENENTECH INC |
发明人 |
AASAA DEII REBINSON;JIENII PIII MAZAA |
分类号 |
C12N5/10;C07K14/62;C07K14/82;C12N9/64;C12N9/72;C12N9/88;C12N15/09;C12N15/67;C12N15/85;C12P21/00;C12Q1/04;C12Q1/68 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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