| 摘要 |
<p>Novel amide compounds of the formula: <CHEM> wherein R<1> is a hydrogen, a lower alkyl, acetyl, or propionyl group; R<2> is a hydrogen or chlorine atom; R<3> is a hydrogen atom or a group of the formula -CO2R<6> (wherein R<6> is a hydrogen atom, a lower alkyl group or an alkali metal); R<4> is a hydrogen atom, a trifluoromethyl, cyano or an aminocarbonyl group, or a group of the formula -CO2R<7> (wherein R<7> is a hydrogen atom, a lower alkyl group, or an alkali metal); R<5> is a hydrogen atom, or a group of the formula -CO2R<8> (wherein R<8> is a hydrogen atom, a lower alkyl group, or an alkali metal), which have excellent anti-allergic activity and are useful for the prophylaxis and/or treatment of various allergic diseases, and a pharmaceutical composition containing the amide compound as set forth above as an active ingredient.</p> |
