| 摘要 |
PURPOSE:To obtain the above compound useful as an intermediate for medicines or agricultural chemicals in high yield and purity in a short process using an inexpensive raw material, by dehydrohalogenating 2,2,6,6- tetrahalocyclohexanimine derivative as a raw material. CONSTITUTION:A 2,2,6,6-tetrahalocyclohexanimine derivative expressed by formula I [R is H, alkyl or (substituted) aromatic group; X is halogen: is dehydrohalogenated in the presence or absence of a basic catalyst, such as NaOH, or by thermal decomposition to afford the aimed compound expressed by formula III useful as a medicine or agricultural chemical, especially as an intermediate for substituted phenylacetic acids expressed by formula II (R<1> and R<4> are lower alkyl, lower alkoxy or halogen having an atomic number of up to 35 or CF3; R<2> and R<3> are H or groups except CF3 in R<1> and R<4>; R<5> and R<6> are H, lower alkyl or benzyl). Furthermore, a solvent, such as chlorobenzene, is used to efficiently advance the dehydrohalogenating reaction. |
