发明名称 |
PROCESS FOR PURIFYING GROWTH HORMONE-LIKE MATERIALS |
摘要 |
<p>A process is provided for separating impurities from an impure mixture containing growth hormonelike material, which comprises: (1) applying said mixture to a reverse phase macroporous acrylate ester copolymer resin support at a pH of from about 7 to about 9; and (2) eluting said growth hormone-like material from said support with an aqueous eluant having a pH of from about 7 to about 9 and containing from about 20% to about 80% by volume of an organic diluent selected from the group consisting of acetone, acetonitrile, and a combination of acetone and acetonitrile.</p> |
申请公布号 |
CA1253997(A) |
申请公布日期 |
1989.05.09 |
申请号 |
CA19860505535 |
申请日期 |
1986.04.01 |
申请人 |
LILLY (ELI) AND COMPANY |
发明人 |
GRINNAN, EDWARD L.;LOGSDON, EDWARD E. |
分类号 |
G01N33/74;B01D15/00;B01D15/08;C07G15/00;C07K1/16;C07K1/20;C07K14/435;C07K14/575;C07K14/61;C07K14/62;C12N9/00;G01N30/26;G01N30/88;(IPC1-7):C07K3/12;C07K7/10;C07K7/40 |
主分类号 |
G01N33/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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