USE OF CYCLIC BIOISOSTERES OF PURINE SYSTEM DERIVATIVES FOR THE TREATMENT DISEASES CAUSED BY DISORDERS OF NITRERGIC AND DOPAMINERGIC SYSTEMS

摘要

The invention relates to compounds of general structural formula (I), wherein R= formula (II), Li, Na, K; R<1>= -H, -NH2, -Br, -Cl, -OH, -COOH; B=-N=,-CH=, Z=-CH=,-N=; A=-N at B= -N=, Z=-CH-; A=-CH = at B= -N=, Z;=-CH-; A=-CH = at B= -N=, Z=-N=; A=-CH = at B=-CH=, Z=-CH=; A=-CH = at B=-CH=, Z=-N= and to the pharmacologically acceptable salts thereof used in the form of an active ingredient exhibiting an activity with respect to nitrergic and/or dopaminergic systems for pharmacological compounds in the form of a neuroprotector, for improving a cognitive function, normalising a psychophysiological state and for treating a large range of neuropsychic and cardiovascular diseases, and diseases caused by a substance abuse and by a hyperactive immune system of mammals including a human being.