摘要 |
<p>A process for the synthesis of glutamic acid intermediate from an acrylate, amide and carbon monoxide and hydrogen by reacting them in the presence of a catalyst comprising a cobalt-containing compound, a bis-phosphine ligand and a solvent at a pressure of at least 500 psi and a temerpature of at least 25 DEG C and thereafter extracting the glutamic acid.</p> |