发明名称 |
Inhibition of allergic contact dermatitis by N-L-alpha-aspartyl-L-phenylalanine 1-methyl ester |
摘要 |
It has now been found that N-L-alpha-aspartyl-L-phenylalanine 1-methyl ester (APM) and/or one of its lower alkyl derivatives can be used to treat allergic contact dermatitis associated with irritating oils such as catechol-containing plant-derived antigens such as poison ivy, poison oak, poison sumac and Asian lacquer tree and oils containing capsaicin. Topical application of APM and/or derivative can reduce or alleviate the symptoms associated with irritation of the skin and/or mucous membranes caused by contact or inhalation of these oils or fumes from burning vegetation containing these oils.
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申请公布号 |
US7288527(B2) |
申请公布日期 |
2007.10.30 |
申请号 |
US20050106201 |
申请日期 |
2005.04.14 |
申请人 |
OKLAHOMA MEDICAL RESEARCH FOUNDATION |
发明人 |
MANION CARL V. |
分类号 |
C07K5/06;A61K9/00;A61K31/197;A61K31/216;A61K38/04;A61K38/05;A61K47/06 |
主分类号 |
C07K5/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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