发明名称 |
PROCESS FOR PREPARATION OF A SOLID FORM FOR ORAL USE BASED ON NIFEDIPINE WITH CONTROLLED RELEASE OF THE ACTIVE SUBSTANCE |
摘要 |
<p>Process for preparation of a solid administration form for oral use based on nifedipine with controlled release of the active substance, characterized by the fact that a mixture of nifedipine crystals having a specific surface area between 0.1 and 0.4 m2/9 is prepared, said mixture of crystals is blended with an equal amount by weight of auxiliary vehicle substances, and the resulting mixture so obtained is applied on spheroids of inert substances, by means of suitable binders, in coating pans.</p> |
申请公布号 |
CA1253079(A) |
申请公布日期 |
1989.04.25 |
申请号 |
CA19850490628 |
申请日期 |
1985.09.12 |
申请人 |
GIUDICE, VITTORIO;RAVELLI, VITTORINO |
发明人 |
GIUDICE, VITTORIO;RAVELLI, VITTORINO |
分类号 |
A61K31/455;A61K9/16;A61K9/50;A61K9/52;A61K31/44;(IPC1-7):A61K31/44 |
主分类号 |
A61K31/455 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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