发明名称 COMPUESTO PEPTIDICO; COMPUESTO PEPTIDICO CON AL MENOS UN APTAMERO; CONJUNTO DE ELEMENTOS PARA PREPARAR PREPARACION RADIOFARMACEUTICA; METODOS PARA PRODUCIR DICHOS COMPUESTOS; USO DE DICHOS COMPUESTOS PARA EL DIAGNOSTICO Y/O TERAPIA DE ENFERMEDAD PROL
摘要 The object of the present invention is solved by compositions of peptide linkers and their use for synthesis and annealing of aptamer oligonucleotides in form of dimers. The present invention in particularly provides said compositions for the use as a diagnostic and/or therapeutic agent. In another preferred embodiment the present invention relates to a kit for preparing a radiopharmaceutical preparation, said kit comprising a vial comprising a quantity of the compound according to the invention. A further preferred embodiment of the present invention relates to methods of producing said compounds, comprising synthesis of said compound in an automated peptide synthesizer. In another preferred embodiment the present invention concerns the use of said compounds according to the present invention for the manufacture of a medicament, preferably for diagnosis or therapy of proliferative diseases. In a further preferred embodiment the present invention concerns methods for treating or diagnosing patients administering or utilizing the compounds according to the present invention.
申请公布号 CL2007002576(A1) 申请公布日期 2008.05.23
申请号 CL20070002576 申请日期 2007.09.05
申请人 BAYER SCHERING PHARMA AKTIENGESELLSCHAFT 发明人 MATTHIAS FRIEBE, ANDREW STEPHENS, ANANTH SRINIVASAN, MAREN HECHT.
分类号 A61K38/00;A61P35/00;C07K7/00 主分类号 A61K38/00
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