发明名称 CRYSTALLINE FORMS OF HISTONE DEACETYLASE INHIBITORS
摘要 The application is related to polymorphs and salts of compounds having the formulae: Compound (I) N-(2-Aminophenyl)-4-((5,6-dimethoxy-2H-indazol-2-yl)methyl)benzamide Compound (II) 4-((6-Acetamido-2H-indazol-2-yl)methyl)-N-(2-aminophenyl)benzamide Compound (III) 1-(4-(2-Aminophenylcarbamoyl)benzyl)-N-ethyl-1H-pyrazole-4-carboxamide Also provided are novel methods for the preparation of the polymorphs of Compound (I), and kits and articles of manufacture of the compositions, and methods of using the compositions to treat various diseases.
申请公布号 WO2008089436(A3) 申请公布日期 2008.12.24
申请号 WO2008US51481 申请日期 2008.01.18
申请人 TAKEDA SAN DIEGO, INC.;HAYES, PATRICK D.;ISBESTER, PAUL;MOBELE, BINGIDIMI I.;PALMER, GRANT;SALSBURY, JONATHON S.;SUN, XUFENG;ULYSSE, LUCKNER 发明人 HAYES, PATRICK D.;ISBESTER, PAUL;MOBELE, BINGIDIMI I.;PALMER, GRANT;SALSBURY, JONATHON S.;SUN, XUFENG;ULYSSE, LUCKNER
分类号 C07D231/14;A61K31/415;A61K31/416;A61P35/00;C07D231/56 主分类号 C07D231/14
代理机构 代理人
主权项
地址