PERORAL DRUG FORM COMPRISING DIENOGEST AND ETHINYL ESTRADIOL FOR CONTRACEPTION
摘要
An oral drug form for contraception comprises as one active component 17a-cyanomethyl-17-ß-hydroxyestra-4,9-dien-3-one (dienogest) in a daily dosage of equal to or less than 2.0 mg and as other active component 17a-ethynyl estradiol (ethinyl estradiol) in a daily dosage of less than 0.03 mg together with one or more pharmaceutically acceptable carriers. The active ingredient dienogest is present in crystalline form with an average particle size of from 25 to 70 µm. The active ingredient ethinyl estradiol is introduced in micronized form or as ethanolic solution during the granulation.
申请公布号
WO2008017331(A3)
申请公布日期
2009.01.08
申请号
WO2007EP03662
申请日期
2007.04.26
申请人
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT;GERECKE, HAGEN;LADWIG, RALF;WIESINGER, HERBERT;FRICKE, SABINE;BUSKE, ALEXANDER
发明人
GERECKE, HAGEN;LADWIG, RALF;WIESINGER, HERBERT;FRICKE, SABINE;BUSKE, ALEXANDER