发明名称 PURIFICATION OF MONOMERIC INTERFERON
摘要 <p>Fast moving monomers of alpha-2 interferon (''IFN-alpha-2'') are purified from slow moving monomers and oligomers of interferon and from noninterferon proteins using a combination of immunoaffinity chromatography, reverse phase HPLC, cation exchange chromatography, and gel filtration. Two fast monomer forms, FMM1 and FMM2, are further distinguished on the basis of charge and hydrophobicity and FMM2 is obtained in essentially homogeneous form with respect to size, hydrophobicity and charge.</p>
申请公布号 WO1989003225(A1) 申请公布日期 1989.04.20
申请号 US1988003409 申请日期 1988.10.03
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