发明名称 |
CORRECTOR OF CYTOSTATIC POLYCHEMOTHERAPY |
摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to correctors of cytostatic polychemotherapy. As corrector claimed is use of betulonic acid -alanylamide of formula (I): which potentiates anti-tumor effect and antimetastatic activity of polychemotherapy (PCT), demonstrates antioxidative and cytoprotecting activity at background of tumor PCT, and also produces anti-toxic impact when complex of cytostatic medications is introduced into organism. Compound (I) is synthesised from plant betulin truterpenoid. ^ EFFECT: obtaining corrector of cytostatic polychemotherapy. ^ 1 cl, 9 ex, 12 tbl |
申请公布号 |
RU2353623(C1) |
申请公布日期 |
2009.04.27 |
申请号 |
RU20070134627 |
申请日期 |
2007.09.17 |
申请人 |
NOVOSIBIRSKIJ INSTITUT ORGANICHESKOJ KHIMII IM. N.N. VOROZHTSOVA SO RAN (NIOKH SO RAN) |
发明人 |
TOLSTIKOVA TAT'JANA GENRIKHOVNA;TOLSTIKOV GENRIKH ALEKSANDROVICH;SOROKINA IRINA VASIL'EVNA;SHUL'TS EHL'VIRA EHDUARDOVNA;PETRENKO NATAL'JA IVANOVNA;SALAKHUTDINOV NARIMAN FARIDOVICH |
分类号 |
A61K31/56;A61P35/00;C07J53/00;C07J63/00 |
主分类号 |
A61K31/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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