| 发明名称 |
COMPOSITIONS AND METHODS FOR TREATING HYPERKALEMIA |
| 摘要 |
The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance. |
| 申请公布号 |
US2016175344(A1) |
申请公布日期 |
2016.06.23 |
| 申请号 |
US201615052186 |
申请日期 |
2016.02.24 |
| 申请人 |
Ardelyx, Inc. |
发明人 |
Charmot Dominique;Davidson James P.;Lin Fangling;Jacobs Jeffrey W.;Blinova Natalia;Labonte Eric;Langsetmo Ingrid;Blanks Robert C. |
| 分类号 |
A61K31/795;B01J39/20 |
主分类号 |
A61K31/795 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A calcium salt of a crosslinked potassium binding polymer having the following structure:or a pharmaceutically acceptable salt thereof,
wherein the mole ratio of m to n is from about 70:1 to about 60:1; and wherein the crosslinked potassium binding polymer is characterized by a crosslinking of about 1.8%, wherein the term about means ±10%. |
| 地址 |
Fremont CA US |
