| 摘要 |
PURPOSE:To obtain a remedy for hyperkeratosis, having remedying effect against hyperkeratosis, low toxicity and high safety, by using (6)-shogaol as an active component. CONSTITUTION:The objective remedy contains, as an active component, (6)- shogaol of formula [1-(4-hydroxy-3-methoxyphenyl)-(E)-4-decen-3-one] having central nervous suppressing action and analgesic action, etc., and existing in KANKYO (dried rhizome of Zingiber officinale) or SHOKYO (raw rhizome of Zingiber officinate) which are Chinese herb drugs compounded in Chinese drug formulations SAIKO-KEIHI-KANKYO-TO, KOSEIRYU-TO, etc. The compound of formula is administered to animal or human as it is or together with conventional drug-preparation carrier. To attain the expected effect as a peroral drug, it is preferable to administer 20-80mg of the compound of formula for adult daily in several divided doses. several times a day. |
