发明名称 |
TISSUE-ENGINEERED SILK ORGANS |
摘要 |
This invention relates to a lamellae tissue layer, comprising a grooved silk fibroin substrate comprising tissue-specific cells. The silk fibroin substrates provides an excellent means of controlling and culturing cell and extracellular matrix development. A multitude of lamellae tissue layers can be used to create a tissue-engineered organ, such as a tissue-engineered cornea. The tissue-engineered organ is non-immunogenic and biocompatible. |
申请公布号 |
EP2129772(B1) |
申请公布日期 |
2016.07.27 |
申请号 |
EP20080730804 |
申请日期 |
2008.02.27 |
申请人 |
TRUSTEES OF TUFTS COLLEGE |
发明人 |
KAPLAN, DAVID L.;OMENETTO, FIORENZO;MARCHANT, JEFFREY;PANJWANI, NOORJAHAN;LAWRENCE, BRIAN |
分类号 |
C12N5/00;A61L27/38;C12N5/071 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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