IDENTIFICATION OF TUMOR ASSOCIATED CELL SURFACE ANTIGEN FOR DIAGNOSIS AND THERAPY

摘要

PROBLEM TO BE SOLVED: To provide a method of stimulating or increasing proliferation of the cell number of MUC1 expression cells by activating MUC1 receptors on the cells.SOLUTION: An activation method may be carried out by contacting cells with (i) an agent that multimerizes the MGFR portion of MUC1; (ii) an agent that increases the cleavage of MUC1 to a growth factor receptor form; or (iii) a ligand that activates the MGFR portion of the MUC1 receptor. The cells may be non-tumorous cells, preferably are immature cells, such as stem cells, progenitor cells, endometrial cells, neutrophil precursors, and neutrophils.SELECTED DRAWING: Figure 14