发明名称 |
Oral and dental hygiene preparations |
摘要 |
Oral and dental hygiene preparations containing quaternary ammonium compounds of the formula <IMAGE> (I) wherein R1 is an n-alkyl group, preferably containing from 8 to 12 carbon atoms, R2 is hydrogen, a CH3-group or a CH2OH-group and R3 is a CH3-group or a group of the formula -CH2-CH(OH)-R2, A is an inorganic or organic acid anion and n is the basicity of the anion. The quaternary ammonium compounds of formula I can have a plaque inhibiting effect and show only slight antimicrobial activity. R1 is preferably an n-decyl group, R2 is hydrogen and R3 is a CH3-group or a 2-hydroxyethyl group. The oral and dent al hygiene preparations also preferably contain fluorides and/or organophosphonates as the anion A.
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申请公布号 |
US4820507(A) |
申请公布日期 |
1989.04.11 |
申请号 |
US19870018762 |
申请日期 |
1987.03.02 |
申请人 |
HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN |
发明人 |
KLUEPPEL, HANS-JUERGEN;PLOEGER, WALTER;RUTZEN, HORST;LEHMANN, RUDOLF |
分类号 |
A61K8/40;A61K8/25;A61K8/26;A61K8/41;A61K8/55;A61Q11/00;(IPC1-7):A61K7/22;A61K7/16;A61K7/24 |
主分类号 |
A61K8/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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