发明名称 METHOD FOR DETECTING VIRUS BY USING LIPOSOME OR LIPOSOME-POLYMER HYBRID
摘要 The present invention relates to a method for detecting a virus by using a liposome or a liposome-polymer hybrid and, more specifically, to a method for detecting a virus by making a liposome or a liposome-polymer hybrid, both of which contain a chromogenic substrate, come into contact with a sample assumed to contain a virus, and then detecting whether there is a virus, through color development according to whether there is an emission of the chromogenic substrate, which is contained in the liposome or the liposome-polymer hybrid, by the contact made therebetween. According to the present invention, the method for detecting a virus by using a liposome or a liposome-polymer hybrid allows a virus to be easily detected with the naked eye. Particularly, when using a liposome or a liposome-polymer hybrid, both of which contain hydrophobic 3,3',5,5'-tetramethyl bezidine (TMB) or iodine, which are chromogenic substrates, the stability to natural color development by oxygen or a chemical reaction is high since TMB or iodine does not leak to the outside of the liposome or the liposome-polymer hybrid. Additionally, it was shown that TMB or iodine contained in the liposome or the liposome-polymer hybrid is discharged and a virus detection signal to be generated by a reaction with HRP or starch, both of which are color development inducer materials, is remarkably high when a virus binds to the liposome or the liposome-polymer hybrid through a viral membrane protein.
申请公布号 WO2016137236(A1) 申请公布日期 2016.09.01
申请号 WO2016KR01829 申请日期 2016.02.25
申请人 BIONANO HEALTH GUARD RESEARCH CENTER 发明人 CHUNG, Bong Hyun;BAE, Pan Kee;PARK, Kyung Mi;KIM, Yujeong
分类号 G01N33/569;G01N33/52;G01N33/535 主分类号 G01N33/569
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