发明名称 |
PHARMACEUTICAL COMPOSITIONS OF RECOMBINANT BETA-INTERFERON AND FORMULATION PROCESSES |
摘要 |
Stable pharmaceutical compositions suitable for parenteral administration to animals or humans are prepared comprising a therapeutically effective amount of a recombinant IFN-beta protein dissolved in an inert carrier medium comprising as solubilizer/stabilizer(s) one or more biocompatible non-ionic polymeric detergents or a combination of one or more biocompatible non-ionic polymeric detergents with an additional solubilizing and/or stabilizing agent, such as sodium dodecyl sulfate or glycerol. Said compositions are in liquid form or lyophilized. |
申请公布号 |
WO8902750(A1) |
申请公布日期 |
1989.04.06 |
申请号 |
WO1988US03313 |
申请日期 |
1988.09.26 |
申请人 |
CETUS CORPORATION |
发明人 |
TAFORO, TERRANCE;THOMSON, JODY;SHAKED, ZE'EV;HERSHENSON, SUSAN;THOMSON, JAMES, W.;STEWART, TRACY |
分类号 |
A61K9/00;A61K38/00;A61K38/21;A61K47/10;A61K47/14;A61K47/26;C07K14/565;(IPC1-7):A61K47/00;A61K45/02 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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