发明名称 Imidazoline derivative and method of treating depression therewith
摘要 2-[2-(1,4-Benzodioxanyl)]-2-imidazoline or a non-toxic salt thereof, substantially free of 2-[2-(2-methyl-1,3-benzodioxyl)]- 2-imidazoline or a non-toxic salt thereof. 2-[2-(1,4-Benzodioxanyl)]-2-imidazoline or a non-toxic salt thereof characterised in that the nuclear magnetic resonance spectrum of the compound in a protonated form exhibits multiplets in the region of tau 4.4 and tau 5.4. Process for the preparation of 2-[2-(1,4-benzodioxanyl)]-2-imidazoline, pharmaceutical compositions thereof or of its salts, and their use as presynaptic alpha 2-adrenoreceptor antagonists.
申请公布号 US4818764(A) 申请公布日期 1989.04.04
申请号 US19810230195 申请日期 1981.02.02
申请人 RECKITT & COLMAN PRODUCTS LIMITED 发明人 CHAPLEO, CHRISTOPHER;MYERS, PETER L.
分类号 C07D405/04;A61K31/415;A61K31/4178;A61P3/08;A61P7/10;A61P9/06;A61P9/12;A61P25/00;A61P25/02;A61P25/04;A61P25/24;A61P25/26;C07D319/20;C07D407/06;(IPC1-7):A61K31/415;C07D403/00 主分类号 C07D405/04
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