摘要 |
A vaccine against a DNA virus, for exmaple, Herpes simplex virus, is prepared by incubating a cell sample which has been infected with the virus, releasing the nuclei in the infected cell material from the cytoplasmic fraction of that material, chemically fixing the polypeptide chains in the cytoplasmic fraction, and forming a precipitate which includes the virus antigens in the cytoplasmic fraction, the precipitate providing the active constituent of the vaccine. A characteristic strain of the virus is preferred, and transfers its characteristics to the vaccine so that vaccinated subjects may subsequently be distinguished from infected subjects.
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