| 发明名称 |
Recombinant immunoglobin preparations |
| 摘要 |
Altered and native immunoglobulins, including constant-variable region chimeras, are prepared in recombinant cell culture. The immunoglobulins contain variable regions which are immunologically capable of binding predetermined antigens. Methods are provided for refolding directly expressed immunoglobulins into immunologically active form.
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| 申请公布号 |
US4816567(A) |
申请公布日期 |
1989.03.28 |
| 申请号 |
US19830483457 |
申请日期 |
1983.04.08 |
| 申请人 |
GENENTECH, INC. |
发明人 |
CABILLY, SHMUEL;HEYNEKER, HERBERT L.;HOLMES, WILLIAM E.;RIGGS, ARTHUR D.;WETZEL, RONALD B. |
| 分类号 |
G01N33/531;A61K39/395;C07K7/06;C07K14/00;C07K16/00;C07K16/18;C07K16/30;C07K16/46;C07K19/00;C12N1/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/13;C12N15/63;C12N15/81;C12P21/02;C12P21/08;C12R1/19;G01N33/577;(IPC1-7):C07K15/14;C07K15/06;C12P21/00;C12N15/00;C12N1/20 |
主分类号 |
G01N33/531 |
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