发明名称 |
SUBSTRATES FOR THE ASSAY OF ENZYMES |
摘要 |
Disclosed are reagents for enzyme assay comprising a substrate consonant with a given enzyme to be assayed, labelled with a chromogenic group which, on action of the given enzyme, is liberated to give a coloured product, the chromogenic group being of formula (I), where Aryl is any aryl group, n is 0-3, R and R' are any compatible group, Het is any heterocyclic group capable of extending the delocalisation of electrons from the aryl group and X is O or NR, R being any suitable group that does not hinder enzyme action. Also disclosed are colour enhancing stopping buffers which are suitable for supply as a solution for use in diagnostic kits. |
申请公布号 |
WO8902473(A1) |
申请公布日期 |
1989.03.23 |
申请号 |
WO1988GB00737 |
申请日期 |
1988.09.07 |
申请人 |
KING'S COLLEGE LONDON |
发明人 |
RICHARDSON, ANTHONY, CHARLES;SMITH, BRIAN, VELLENDER;PRICE, ROBERT, GRAHAM;PRAILL, PERCY, FRANCIS, GEORGE |
分类号 |
C07D213/30;C07D215/14;C07D231/26;C07D239/66;C07D277/20;C07D277/36;C07F9/6541;C07H15/26;C12Q1/00;C12Q1/34;C12Q1/42;C12Q1/44;(IPC1-7):C12Q1/00 |
主分类号 |
C07D213/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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