Preparation of hydroxyalkylpiperazinones by reacting an alkylene oxide with decahydropyrazino[2,3-b]pyrazine or its substituted derivatives

摘要

The 4-(2-hydroxyalkyl)-2-piperazinones and their substituted derivatives are prepared by reacting a decahydropyrazino[2,3-b]pyrazine or its substituted derivative having at least one active amine hydrogen, with an alkylene oxide having 2 to 4 carbon atoms.