发明名称 11 beta -(4-isopropenylphenyl)estra-4,9-dienes, their production, and pharmaceutical preparations containing same
摘要 11 beta -(4-isopropenylphenyl)-estra-4,9-dienes of general Formula I <IMAGE> (I) wherein X is an oxygen atom or a hydroxyimino grouping N OH, R1 is a hydrogen atom or a methyl group, R2 is a hydrogen atom or an acyl residue of 1-10 carbon atoms, R3 is a hydrogen atom, the cyanomethyl group, -(CH2)n-, CH2Z, -CH=CH-(CH2)mZ or -C 3BOND C-Y wherein n=0 to 5 and m=1 to 4, Z meaning a hydrogen atom or the OR4 group with R4 meaning a hydrogen atom, an alkyl or alkanoyl group each of 1-4 carbon atoms, and Y meaning a hydrogen, chlorine, fluorine, iodine or bromine atom, an alkyl, hydroxyalkyl, alkoxyalkyl or acyloxyalkyl group each of 1-4 carbon atoms in the alkyl or acyl residue, possess antiprogestational activity.
申请公布号 US4814327(A) 申请公布日期 1989.03.21
申请号 US19870077359 申请日期 1987.07.24
申请人 SCHERING AKTIENGESELLSCHAFT 发明人 OTTOW, ECKHARD;WIECHERT, RUDOLF;NEEF, GUENTER;BEIER, SYBILLE;ELGER, WALTER;HENDERSON, DAVID
分类号 A61K31/565;A61P5/00;A61P13/02;A61P15/00;C07J;C07J1/00;C07J17/00;C07J21/00;C07J41/00;(IPC1-7):A61K31/56 主分类号 A61K31/565
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