发明名称 Treatment for Alzheimer's disease
摘要 Hydroypyridine analogs, Dihydropyridine analogs, Trihydropyridine analogs, Hydropurine analogs, Dihydropurine analogs, Trihydropurine analogs, N,N,N,'-trimethyl-N'-(2-hydroxy-3-methyl-1,3-propanediamine analogs, 1-methyl-3-[N-(4-iodophenyl)-carbamoyl]-1,4-dihydropyridine analogs, that are lipid-soluble with the specific electron charge density and therefore useful for the administration of several compounds that need to penetrate the blood-Brain capilliary barrier. Once inside the brain these compounds under go NAD-NADH reduction thereby providing for a brain serum retention. These compounds having been modified herein to deliver various compounds, some of which are those that are progressively absent during the course of a disease called Alzheimer's Disease.
申请公布号 US4814339(A) 申请公布日期 1989.03.21
申请号 US19860828763 申请日期 1986.02.11
申请人 ADVANCED BIOLOGICS, INC. 发明人 ROTONDO, RICHARD D.
分类号 A61K31/44;(IPC1-7):A61K31/44 主分类号 A61K31/44
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